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The active molecules are purified with hoodia gordonii which are called
p57. These substances are passed to brain. You will be able to ingest lesser amount of food and can reduce the intake of calories.

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Scientists believe that the reason for Hoodia’s appetite suppressing abilities is a molecule called "P57". Normally, when you eat the glucose in your body rises and eventually signals to your brain (the hypothalamus) that you are full. It is believed that "P57" molecule in Hoodia mimics the effect that glucose has on your brain, telling part of your brain (the Hypothalamus) that you feel full.