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Other signs which can move with FAP are the pigmented lesions of the retina, of the cysts of jaw, the cysts sebaceous, and the osteomata. The combination of the polyposis, the osteomas, the fibromas and the cysts sebaceous names syndrome of Gardner. Each child of an affected relative has a risk of 50% to inherit gene of the disease. FAP is caused by a change of germline gene of filter of tumour of RPA, located on the tape 5q21. Of the more virulent forms of FAP are associated a change in the exon 15 between code 1250 and 1464, the central portion of gene.
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